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New in Cephalalgia! Migraine is associated with significantly reduced thalamic glutathione (GSH) levels, resulting in decreased GSH/glutamate (Glu) ratios that indicate diminished antioxidant buffering capacity. • This metabolic alteration is present in

The clinical presentation of this condition is diverse, and the intensity of symptoms typically corresponds to the severity of nerve damage

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Cellular GSH levels affect T helper cell maturation [79], T cell proliferation [80], as well as susceptibility to ROS secreted by inflammatory cells